Proteoglycans and glycosaminoglycans: Complex molecules with modulating activity Maryse Delehedde, Stéphane Sarrazin, Estelle Adam, Vincent Motte and Christophe Vanpouille
1
Proteoglycans and glycosaminoglycans: Key players in inflammation Philippe Lassalle, Estelle Adam, Stéphane Sarrazin, Florence Depontieu, Vincent Motte, Christelle Villedieu, Stéphane Lequien, Bogdan Grigoriu, Nathalie De Freitas-Caires, Christophe Vanpouille and Maryse Delehedde
15
Glycomics and angiogenesis: Biological implications and therapeutical exploiting Marco Rusnati, Chiara Urbinati and Marco Presta
33
Anticoagulant heparan sulfate: A regulator of tissue remodeling in reproduction Ariane I. de Agostini
79
HS / protein interactions: Tools to decipher the code Elodie Crublet and Romain R. Vivès
107
Glycosaminoglycans: Synthetic access to their molecular diversity and to bioactive mimics of large fragments David Bonnaffé
133
Screening tools for glycomics Françoise Vinet and Veronique Robert
161
Molecular modeling of glycosaminoglycans and interactions with protein receptors-Methods and progress Anne Imberty and Serge Pérez
185
New surface-based techniques for the analysis of protein-GAG interactions Tim R. Rudd, Carla J. Terry, Chris G. Rees, Richard J. Nichols and David G. Fernig
203
Major applications in therapeutic glycomics-Fibroblast growth factors (FGFs) interactions with GAGs: NMR studies using synthetic oligosaccharides Pedro M. Nieto, Jesús Angulo, Angeles Canales and Jesús Jiménez-Barbero
227
Heparanase as a target for anticancer therapeutics: New developments and future prospects Edward Hammond, Ian Bytheway and Vito Ferro
251
Stromal derived growth factor-1: A target for GAG-based therapies? Estelle Adam, Vincent Motte, Stéphane Sarrazin and Maryse Delehedde
283
Applications in therapeutic glycomics: Example of the cyclophilins as novel inflammatory mediators in rheumatoid arthritis Aurélie Melchior, Agnès Denys, Rachel Pakula and Fabrice Allain
303
The co-factor role of glycosaminoglycans in the activity of hepatocyte growth factor/scatter factor and the possibilities for therapeutic inhibition Malcolm Lyon
317
Glycosyltransferases initiating glycosaminoglycan synthesis: Targets in therapeutic glycomics Mohamed Ouzzine, Jean-Claude Jacquinet, Patrick Netter Jacques Magdalou and Sylvie Fournel-Gigleux
351
Involvement of O-linked N-acetylglucosamine in type-2 diabetes, neurological disorders and cancer Tony Lefebvre, Vanessa Dehennaut, Céline Guinez and Jean-Claude Michalski
377
