Title

• Protein kinase C, an antiangiogenic and antitumor target  
  Beverly A. Teicher

    1

• Stroma, microenvironment and radiation carcinogenesis  
  Hellen A. Oketch-Rabah and Mary Helen Barcellos-Hoff

    29

• Sphingomyelin metabolism: Implications for cell signaling and drug uptake  
  Marcel Verheij and Wim J. van Blitterswijk

    55

• Radiation-induced bystander effects in cancer  
  Hongying Yang and Kathryn D. Held

    73

• Exosomes in cancer and their role in tumor escape  
  Theresa L. Whiteside

    89

• Molecular cytogenetic characterization of primary and matched metastatic and radioresistant head and neck squamous cell carcinoma-derived cells  
  Bassem R. Haddad, Theresa L. Whiteside and Usha N. Kasid

    111

• Antisense inhibition of Raf-1 is associated with differential modulation of antioxidant enzymes and enhanced output of steady state and TNF-a-stimulated hydrogen peroxide  
  Usha Kasid, Fuh-Han Wang, Theresa L. Whiteside and Linda B. Clerch

    125

• Tyrosine kinase inhibitors against childhood acute lymphoblastic leukemia  
  Fatih M. Uckun and Heather E. Tibbles

    141

• Targeting Janus kinase 3 for chemoprevention of colorectal cancer  
  Heather E. Tibbles and Fatih M. Uckun

    163

• Therapeutic small interfering RNAs: Delivery, targeting and innate immunity  
  Mouldy Sioud and Sébastien Wälchli

    175

• New directions in development of pharmacological countermeasures for the acute radiation syndrome  
  Mark H. Whitnall and Terry C. Pellmar

    193

• Tumor oxygenation and cancer therapy  
  Sara Rockwell

    211