Title

• Bile acids and cholangiocyte biology  
  Xuefeng Xia and Gene LeSage

    1

• Role of angiogenesis and angiogenic factors for cholangiocyte growth  
  Carlo Spirli, Luca Fabris, Romina Fiorotto, Massimiliano Cadamuro, Stefano Okolicsanyi and Mario Strazzabosco

    21

• Endocrine regulation of cholangiocyte growth and response to liver injury  
  Domenico Alvaro, Maria Grazia Mancino, Gianfranco Alpini, Antonio Franchitto, Paolo Onori and Eugenio Gaudio

    37

• Nervous modulation of ductal secretion and cholangiocyte hyperplasia  
  Sharon DeMorrow, Heather Francis, Julie Venter, Shelley Vaculin, Bradley Vaculin, Monique Stutes, Steve Tran, Benjamin Perry, Candace Wise, Gianfranco Alpini and Shannon Glaser

    59

• Crosstalk signaling between bile duct epithelia and portal fibroblasts/myofibroblasts  
  Jonathan A. Dranoff

    73

• Bioinformatic approach to cholangiocyte growth  
  Koji Fukushima and Yoshiyuki Ueno

    81

• Ion transporters and cholangiocyte pathophysiology  
  Jesús M. Banales, Jesús Prieto and Juan F. Medina

    101

• Genetics and immunology of primary biliary cirrhosis  
  Pietro Invernizzi, Gianfranco Alpini, Carlo Selmi and M. Eric Gershwin

    131

• Clinical features of cholangiopathies  
  Raoul Poupon

    159

• Current therapies for cholangiopathies  
  Phunchai Charatcharoenwitthaya and Keith D. Lindor

    183

• Ductular reactions during the development of cirrhosis  
  John G. Lunz III, Susan Specht M.S., Kumiko Isse, Andrew Clouston and Anthony J. Demetris

    223

• The role of the cholangiocyte in the hepatopulmonary syndrome  
  Moises Ilan Nevah R. and Michael B. Fallon

    257

• Cholangiociliopathies: Mechanisms of development and therapeutic targets  
  Tatyana V. Masyuk, Anatoliy I. Masyuk and Nicholas F. LaRusso

    269

• Cholangiocarcinoma: Epidemiology, risk factors, and molecular pathogenesis  
  Konstantinos N. Lazaridis

    301

• Cholangiocarcinoma: Are stem cells involved?  
  Malcolm R. Alison

    315

• Nervous and neuroendocrine control of cholangiocarcinoma growth  
  Giammarco Fava, Marco Marzioni and Antonio Benedetti

    325

• Regulators of apoptosis in cholangiocarcinoma  
  Yabing Chen, Pritish Pawar, Nirag Jhala and Jay M McDonald

    337

• Progress in treatment and prevention of cholangiocarcinoma  
  Giammarco Fava, Antonio Benedetti and Domenico Alvaro

    353